You must be 18+ to view this content
Clinical Trial may contain content you must be 18+ to view.
The creator of this page has specified that it contains mature themes and content. Please enter your birthdate to verify you are 18 or older:

Clinical Trial
A downloadable game for Windows and macOS
A suspense tale about signing up to test psychiatric drugs for money and provider-patient relations.
RPGMaker story driven game. Visual novel you can walk around in. Reality testing simulator.
Intended for mature audiences only. Contains horror elements and disturbing themes.
Approximate playtime: 3 hours. There are two endings.
Click for warnings/spoilers:
Pixelated gore. References to sexual assault.
Click for credits:
Art, story, programming by homie
Angel's art by peachy
Music by desesseintes
Sound effects from Pixabay
RPGMaker plugins by Team VisuStella (Yanfly, Arisu, Olivia, Irina) and Synrec/Kylestclr
Click for controls/options:
Controls:
Arrow keys to move
Z/space/return to interact
X/escape to open and close menu
Hold space/return to speed up dialogue
Hold shift to move faster
Options:
BGM - Background Music
BGS - Background Sound
ME - Musical Effects (unused)
SE - Sound Effects
Click for fan translations:
(日本語 | 한글 | 中文 | PT-BR | Русский | español | Türkçe | Український | Furry)
非公式日本語訳 / Japanese 1 | Japanese 2
비공식 한글 번역 / Korean
民间简体中文汉化 / Chinese
Tradução não-oficial em PTBR | Brazilian Portuguese
Фанатский русский перевод | Russian (Itchio)
Traducción no oficial al español | Spanish
Fan yapımı Türkçe yama | Turkish
Фанатський український переклад | Ukrainian
Furry mod | Furry
| Status | Released |
| Platforms | Windows, macOS |
| Rating | Rated 4.8 out of 5 stars (1,086 total ratings) |
| Author | homie |
| Genre | Visual Novel |
| Made with | RPG Maker |
| Tags | Horror, Psychological Horror, RPG Maker |
| Average session | A few hours |
| Languages | English |
| Inputs | Keyboard |
Install instructions
Instructions for Windows:
- Download ZIP
- Extract all
- Open folder
- Open Game.exe
Instructions for Mac:
NOTE: Archive Utility, Apple's built-in application, may not extract the ZIP properly. Please use The Unarchiver or another data decompressor.
- Download ZIP
- Right click —> Open With —> The Unarchiver
- Open Game
- If you see "Error: Please move the Game.app to a different folder," drag the Game icon somewhere other than where it was downloaded to (e.g. your desktop or any other folder)
- If you see "Cannot be opened because the developer cannot be verified," right click Game —> Open —> Open
Instructions for Android:
While Clinical Trial is not ported for Android, some have been able to run the game using a third party application called Joiplay as described in the instructions below.
Please keep in mind RPGMaker MZ games are not intended to run on a phone and some lag should be expected. I would strongly recommend running the game on a computer instead if possible.



Development log
- March 2025 Game UpdateMar 23, 2025


Comments
Log in with itch.io to leave a comment.
I don't think I've ever been witness to such richness and central focus on character in a game before playing this. My appreciation for this game goes beyond any pithy accolades such as "the writing is good." This is a sheer masterpiece of character development and naturalistic dialogue in concert with a beautiful handling of some sensitive subject matter. The writing has such versamilitude and credence that lends itself to one of the most intimate experiences I have ever had playing a visual novel, it also helps that I relate deeply to both characters' intrapersonal struggles, as im sure most people with ADHD will find. This work of art elegantly and beautifully captures that feeling of finding yourself completely isolated, emotionally and physically, and how wrought with suffering it can be to find yourself constantly entrenched in self-abuse. Excellent game that deserves every one of the five stars I gave it, would support the developer if I could to incentivise them to keep making amazingly visceral and intimate stories like this one.
god i wish that were me
I enjoyed this so much this sh*t is wild.
It is absolutely criminal that this game is free. Please, please post a paypal link or something so I can pay for this experience. This is genuinely one of the best games I've ever played.
I was on the edge of my seat the entire time. There were at least a dozen lines that made my jaw drop. I was excited for every single line of dialogue, I never stopped wanting to see what was going to happen next.
Angel and Lee are such beautiful broken people. Thank you so much for telling their story.
SPOILERSS
I don't usually leave comments on games I play.. but this game made me want to. I actually enjoyed it-- heck I love it! I guess as someone who also experienced what Angel has gon through, it healed something in me. Seeing how Lee took matters into his hands, it geniunely had me on tears. I wish someone has done something like that for me too;;
Absolutely loved the game, but the second ending kinda felt... ''Unnatural'', I guess? It just felt like angel accepting lee was a bit forced. Nonetheless it was a great experience, would recomend!
I loved this game!
This was a great experience, thank you for creating this homie. Please ignore all the pearl clutchers, your art is great and I would love to see more of it
Man i really want to play this but i have an android
You can play it with maldives or joiplay emulator
this is my favorite game omg i can't express how much i love this game
I liked this game a lot! :D
When getting the good ending, I thought the two animated bonus sequences were really cool and cute. I heavily recommend playing this game
Can't really stop thinking about this game. Forgot what that felt like for a while, it's a good feeling
Hello, I am sorry if this is spam. I am trying to get into contact with Homie on behalf of a friend who would like permission for a project they want to do related to clinical trial.
Also was playing through the game with this friend the other night and we had a great time.
Thank you for making this game. It has been a great source of conversation between my friend and I.
Fanworks are welcome. If the project uses game assets, credit the appropriate person as listed in the 'Credits' section on this page.
You said in another comment your friend wants to animate something. I can't see why they would need permission to make a fan animation. People generally don't get permission to make fanart.
Thanks for playing!
I hope that one day there will be an Android version.
Did you try following what's written in the 'Instructions for Android' tab on this page?
this certainly has been a clinical trial
Very Interesting game. I liked most of the large-scale art and I thought it was cool how the character portraits during dialogue had so many expressions they were almost animated, with even more variants on top of those (the rooftop scene is a very good example of this), though having two character portraits on opposite sides of the screen at the same time made it difficult to focus on the expressions and dialogue.
[Keep in mind there are spoilers past this point...]
The writing had me immersed and I was able to connect with the two main characters. The dialogue and the way the relationship between the two characters grew felt natural to me, Angel and Lee have a good mix of similarities and differences that make them work well together.
I thought the plot twist threw a lot of what I liked about the characters' relationship out the window and I felt there was an unintentional change in Lee's personality that made him seem a little more irrational and uncaring than I think he would be. However, the whole section starting from the discovery of the shrine was so insane, it gets crazier and crazier with each reveal which I thought was hilarious.
I liked both endings, they felt unsatisfying in the right way. Ending 1 felt like the only reasonable option, it was pretty chilling and I like how it gives a little more insight into the dark side of Lee and you're left to draw your own conclusions on what happens to Angel next. Ending 2 is very, very interesting to me. It's like a messed up parody of a romcom where everything goes right and they all live happily ever after, which made a really discomforting juxtaposition of this happy ending and the terrible circumstances that preceded it. It's like a "what if?" where everything goes right but I'm left with a sense of dread because it's completely unrealistic. It's the happy ending I wanted, but it didn't feel like how things would have or should have gone down. Is that feeling what you were going for?
I don't regret playing this myself in the slightest, it's left me with a lot to think about. I definitely enjoyed my time with it.
Hello homie, im leaving this comment to hope to get in contact with you for a friend. They have plans to animate some clinical trial but would like to be in contact for permission.
gotta be one of my top favs... theres smth so comforting and real about homies art and the char dialogue makes me so sdkjsajkdj!!! love seeing angel's and lee's dynamic omg theyr so freakin cute
it's as if this game was made for me in a lab. i found it through homie's art while desperately googling for more because homie's art was also seemingly made for me in a lab. i could go on and on so i won't because it would be strange. thank you for making things
I get at least one spam comment that says "Update: New Version - Click Here" every day on here. I report them once I see them. Please disregard them. Thanks.
- Homie
Genuinely adore this game and replay it when im saddies. It's so kind, for lack of a better word. It is so... gentle. To me. Anyways time for playthrough 4
so peak
BEST VISUAL NOVEL GAME EVER!
ending one made me cry, i love this game and its characters quite a lot. i like the development on Lee going from super perfect and straight cut to having his own flaws and past
Hey homie and every dev of this game, thank you for making such masterpiece.
And after playing it halfway through the game, i noticed the deep, underlying themes you were exploring right away, the weight of being misunderstood, the extreme desolation and repression, and the whole “don't care if its right or wrong as long as he loves me wholeheartedly,” motif. By the time I reached the basement, choosing 'Accept' felt like my only resonable choice to that specific brand of isolation, of why a soul would choose that sanctuary over a cold reality, it's too relatable.
and nevertheless, they really hit it off during the first few sessions. (blue bandages, talking about the paintings on the wall) <3 !!
It is rare to see the desperate craving for connection handled with such clinical and emotional precision.
One small wrinkle on the plot regards after the discovery of the shrine though, but ofc still A hauntingly accurate piece of work!! The 'Reality Testing' was a success :D Thank you for writing an emotional truth that feels so terrifyingly real.
<3<3
i also loved this game with my entire freaking soul. i'd give my life for this game. just absolutely amazing
Awesome game, love how you dealt with and explained everything (not spoiling anything)
Question tho, is there a place to get the soundtrack?
absolute peak. I think the characters are very well-written and I really liked the art style
this game was so good ohmygod
I watched my boyfriend play this over Discord and even I just watching was so invested in everything
How do you full screen 💔✌️
Did you try F4 on Windows, possibly function key and F4 at the same time (Fn+F4)?
OMG TYY
I loved it !!! >< made me cry lolll
Absolutely loved this :)
I played this game in one sitting and couldn’t put it down. The game has this quiet tension that grows little by little, and the mix of walking around and reading dialogue works well together. It feels quiet but still tense. The two main characters stand out a lot. Their talks feel real, and their small habits and actions make them easy to connect with. The writing is simple but strong, and what hit me most was how my view of the characters kept shifting while I played. Sometimes I felt safe, and other times I couldn’t tell what would happen next.
SPOILER. I got to see both endings, though I felt more satisfied with the one where things turned out well for the characters. It’s only a few hours long, but it leaves a mark, and I really enjoyed the bonus scenes too!
Goated game, gave me a lot to think about
OMG my name is also Angel, I'm neurodivergent and I worked 7 years in food service too haha!
I loved this game btw.